Медицинская литература


Screening of Anticancer Metabolites Produced by Endophytic Fungi

5,68600 руб.

Рубрика: Генетика. Микробиология

Автор(ы): Fatma Salem and Ahmed Abdel-Azeem

Язык: Английский

Издательство: LAP Lambert Academic Publishing

ISBN: 9783659536977

Баркод: 9783659536977

Год: 2014

Наличие книги: Отгружается в течение двух недель

Дополнительные характеристики

Страниц: 144

Описание книги

The annual death toll from cancer is expected to rise to 17.5 million by 2050. The anticancer drugs show nonspecific toxicity to proliferating normal cells, possess enormous side effects, and are not effective against many forms of cancer. The anticancer properties of several secondary metabolites from endophytes have been investigated recently. In the continuing search for biologically active natural products from Egyptian endophytic mycobiota, Fatma screened endophytic fungi from different ecological habitats in Egypt especially those producing anticancer metabolites. She found that metabolic extracts of endophytic Trichothecium roseum (23A-SCUF) isolated from Origanum syriacum L. significantly decreased tumor cells of (MCF-7) by 48-71%, without alter liver or kidney functions in vivo. She applied three strategies to for conservation of Egyptian endophytic mycobiota: 1- by conserving the habitats of in Saint Katherine Protectorate through volunteers, 2- in situ conservation of...

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