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Epidemiology of Peste des Petits Ruminants in Ethiopia

7,11000 руб.
ОСТАВИТЬ ЗАЯВКУ

Рубрика: Генетика. Микробиология

Автор(ы): Abraham Gopilo

Язык: Английский

Издательство: LAP Lambert Academic Publishing

ISBN: 9783659612435

Баркод: 9783659612435

Год: 2014

Наличие книги: Отгружается в течение двух недель

Дополнительные характеристики

Страниц: 220

Описание книги

Peste des petits ruminants is an acute and highly contagious viral disease of small ruminants which is characterized by high fever,ocular and nasal discharge,pneumonia,necrosis and ulceration of the mucuous membrane and inflammation of the gastro-intestinal tract leading to severe diarrhoea and high mortality. Clinical PPR is confirmed in Ethiopian goats, however, its circulation in other animals has never been described. In this work, we showed that antibody seroprevalence in camel, cattle, goat and sheep confirmed natural transmission in these animals without clinical disease. Virulence of PPRV was monitored in cell culture system and the use of virus specific monoclonal antibodies that enabled to detect differences in virulence between PPRV and RPV. The difference in infectivity of PPRV and RPV may have depended on the H protein epitopes and their cellular receptors. We decided to compare the amino acid epitope of H protein of PPRV with that of other morbilliviruses. We have...

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